منابع مشابه
Early antibiotic treatment failure.
There is no consensus on the definition of treatment failure. It is usually based on clinical signs, although microbiological and other biological markers may prove of value in the future. The major risk factors associated with treatment failure include an inadequate antimicrobial spectrum of the prescribed antibiotic and lack of, or insufficient, control of the source of the infection. In cert...
متن کاملAntibiotic Treatment in Premature Rupture of Pre-Term Bag
بیش از ۳۰ سال پیش لبهرز (۲) و همکارانش مطالعه آنتی بیوتیک تراپی را در پارگی زودرس کیسه آب شروع نمودند. انگیزه این بررسی، تشخیص عوارض مربوط به مادر و نوزاد در PROM بوده است، تاکنون تحقیقات وسیعی برای پی بردن به علت PROM و تعیین خط مشی هایی برای کسب نتیجه مطلوب صورت گرفته است. علیرغم این مساله PROM هنوز به صورت یک «معمای مامایی » باقی مانده است.
متن کاملAntibiotic treatment and susceptibility testing.
T he concept of attacking invading microorganisms without harming the host was first introduced by Paul Ehrlich. In 1910 he discovered ‘‘salvarsan’’, which he announced as a magic bullet for the treatment of syphilis. Penicillin, produced by the fungus, Penicillium notatum, was first discovered by Alexander Fleming in 1928, purified by Florey and Chain in 1940, and shown to have wide applicabil...
متن کاملThe Pharmacodynamics of Antibiotic Treatment
We derive models of the effects of periodic, discrete dosing or constant dosing of antibiotics on a bacterial population whose growth is checked by nutrient-limitation and possibly by host defenses. Mathematically rigorous results providing sufficient conditions for treatment success, i.e., the elimination of the bacteria, as well as for treatment failure, are obtained. Our models can exhibit b...
متن کاملEthical dilemmas in antibiotic treatment.
Patients with moderate to severe infections are given less than maximum empirical antibiotic treatment in order to reduce the rise in resistance. This practice involves two ethical dilemmas: whether the danger to a present patient should be increased (even if by a small degree) to benefit future, unidentified patients; and whether this should be done without the consent of the patient, disregar...
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 2006
ISSN: 1540-8140,0021-9525
DOI: 10.1083/jcb.1743rr3